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Silica nanoparticles induce endoplasmic reticulum stress response and activate mitogen activated kinase (MAPK) signalling

Humans may be exposed to engineered silica nanoparticles (SiO(2)-NPs) but potential adverse effects are poorly understood, in particular in relation to cellular effects and modes of action. Here we studied effects of SiO(2)-NPs on cellular function in human hepatoma cells (Huh7). Exposure for 24 h t...

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Detalles Bibliográficos
Autores principales: Christen, Verena, Fent, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5616204/
https://www.ncbi.nlm.nih.gov/pubmed/28959611
http://dx.doi.org/10.1016/j.toxrep.2016.10.009