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Analysis of chromatin accessibility in human epidermis identifies putative barrier dysfunction-sensing enhancers

To identify putative gene regulatory regions that respond to epidermal injury, we mapped chromatin dynamics in a stratified human epidermis during barrier maturation and disruption. Engineered skin substitutes (ESS) cultured at the air-liquid interface were used as a model of developing human epider...

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Detalles Bibliográficos
Autores principales: Lander, Julie M., Supp, Dorothy M., He, Hua, Martin, Lisa J., Chen, Xiaoting, Weirauch, Matthew T., Boyce, Steven T., Kopan, Raphael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617145/
https://www.ncbi.nlm.nih.gov/pubmed/28953906
http://dx.doi.org/10.1371/journal.pone.0184500