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Analysis of chromatin accessibility in human epidermis identifies putative barrier dysfunction-sensing enhancers
To identify putative gene regulatory regions that respond to epidermal injury, we mapped chromatin dynamics in a stratified human epidermis during barrier maturation and disruption. Engineered skin substitutes (ESS) cultured at the air-liquid interface were used as a model of developing human epider...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617145/ https://www.ncbi.nlm.nih.gov/pubmed/28953906 http://dx.doi.org/10.1371/journal.pone.0184500 |