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Early and late pulmonary effects of nebulized LPS in mice: An acute lung injury model

BACKGROUND AND OBJECTIVE: Acute respiratory distress syndrome (ARDS) has a high mortality rate of 35–46% depending on its severity. Animal models are crucial to better understand the pathophysiology of diseases, including ARDS. This study presents a feasible animal model of acute lung injury (ALI) u...

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Detalles Bibliográficos
Autores principales: de Souza Xavier Costa, Natália, Ribeiro Júnior, Gabriel, dos Santos Alemany, Adair Aparecida, Belotti, Luciano, Zati, Douglas Hidalgo, Frota Cavalcante, Marcela, Matera Veras, Mariana, Ribeiro, Susan, Kallás, Esper Georges, Nascimento Saldiva, Paulo Hilário, Dolhnikoff, Marisa, Ferraz da Silva, Luiz Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617199/
https://www.ncbi.nlm.nih.gov/pubmed/28953963
http://dx.doi.org/10.1371/journal.pone.0185474