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Hypergravity down-regulates c-fos gene expression via ROCK/Rho-GTP and the PI3K signaling pathway in murine ATDC5 chondroprogenitor cells

Chondrocytes are known to be physiologically loaded with diverse physical factors such as compressive stress, shear stress and hydrostatic pressure. Although the effects of those mechanical stimuli onto various cell models have been widely studied, those of hypergravity have not yet been revealed cl...

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Detalles Bibliográficos
Autores principales: Kim, Jeonghyun, Montagne, Kevin, Nemoto, Hidetoshi, Ushida, Takashi, Furukawa, Katsuko S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617206/
https://www.ncbi.nlm.nih.gov/pubmed/28953959
http://dx.doi.org/10.1371/journal.pone.0185394