Class II and IV HDACs function as inhibitors of osteoclast differentiation

Histone deacetylases (HDACs) are negative regulators of transcription and have been shown to regulate specific changes in gene expression. In vertebrates, eighteen HDACs have thus far been identified and subdivided into four classes (I-IV). Key roles for several HDACs in bone development and biology...

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Detalles Bibliográficos
Autores principales: Blixt, Nicholas C., Faulkner, Bora K., Astleford, Kristina, Lelich, Rosemary, Schering, Jacob, Spencer, Ekaterina, Gopalakrishnan, Rajaram, Jensen, Eric D., Mansky, Kim C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617211/
https://www.ncbi.nlm.nih.gov/pubmed/28953929
http://dx.doi.org/10.1371/journal.pone.0185441

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617211/
https://www.ncbi.nlm.nih.gov/pubmed/28953929
http://dx.doi.org/10.1371/journal.pone.0185441

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