Influenza virus differentially activates mTORC1 and mTORC2 signaling to maximize late stage replication

Influenza A virus usurps host signaling factors to regulate its replication. One example is mTOR, a cellular regulator of protein synthesis, growth and motility. While the role of mTORC1 in viral infection has been studied, the mechanisms that induce mTORC1 activation and the substrates regulated by...

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Detalles Bibliográficos
Autores principales: Kuss-Duerkop, Sharon K., Wang, Juan, Mena, Ignacio, White, Kris, Metreveli, Giorgi, Sakthivel, Ramanavelan, Mata, Miguel A., Muñoz-Moreno, Raquel, Chen, Xiang, Krammer, Florian, Diamond, Michael S., Chen, Zhijian J., García-Sastre, Adolfo, Fontoura, Beatriz M. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617226/
https://www.ncbi.nlm.nih.gov/pubmed/28953980
http://dx.doi.org/10.1371/journal.ppat.1006635

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617226/
https://www.ncbi.nlm.nih.gov/pubmed/28953980
http://dx.doi.org/10.1371/journal.ppat.1006635

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