Identification and prioritization of novel anti-Wolbachia chemotypes from screening a 10,000-compound diversity library

Lymphatic filariasis and onchocerciasis are two important neglected tropical diseases (NTDs) that cause severe disability. Control efforts are hindered by the lack of a safe macrofilaricidal drug. Targeting the Wolbachia bacterial endosymbionts in these parasites with doxycycline leads to a macrofil...

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Detalles Bibliográficos
Autores principales: Johnston, Kelly L., Cook, Darren A. N., Berry, Neil G., David Hong, W., Clare, Rachel H., Goddard, Megan, Ford, Louise, Nixon, Gemma L., O’Neill, Paul M., Ward, Stephen A., Taylor, Mark J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617373/
https://www.ncbi.nlm.nih.gov/pubmed/28959730
http://dx.doi.org/10.1126/sciadv.aao1551

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617373/
https://www.ncbi.nlm.nih.gov/pubmed/28959730
http://dx.doi.org/10.1126/sciadv.aao1551

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