Intraductal cisplatin treatment in a BRCA-associated breast cancer mouse model attenuates tumor development but leads to systemic tumors in aged female mice

BRCA deficiency predisposes to the development of invasive breast cancer. In BRCA mutation carriers this risk can increase up to 80%. Currently, bilateral prophylactic mastectomy and prophylactic bilateral salpingo-oophorectomy are the only preventive, albeit radical invasive strategies to prevent b...

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Detalles Bibliográficos
Autores principales: de Groot, Jolien S., van Diest, Paul J., van Amersfoort, Miranda, Vlug, Eva J., Pan, Xiaojuan, ter Hoeve, Natalie D., Rosing, Hilde, Beijnen, Jos H., Youssef, Sameh A., de Bruin, Alain, Jonkers, Jos, van der Wall, Elsken, Derksen, Patrick W.B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617383/
https://www.ncbi.nlm.nih.gov/pubmed/28977823
http://dx.doi.org/10.18632/oncotarget.18490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617383/
https://www.ncbi.nlm.nih.gov/pubmed/28977823
http://dx.doi.org/10.18632/oncotarget.18490

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