Reversal effect of Jagged1 signaling inhibition on CCl4-induced hepatic fibrosis in rats

The role of the Notch ligand Jagged1 in hepatic fibrosis remains to be elucidated. In the current study, we investigated the role of Jagged1 in the activation of hepatic stellate cells (HSCs) and development of hepatic fibrosis in rats. In vitro, Jagged1 in HSCs was downregulated and upregulated by...

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Detalles Bibliográficos
Autores principales: Tang, Guiju, Weng, Zhihong, Song, Jun, Chen, Yixiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper: Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617385/
https://www.ncbi.nlm.nih.gov/pubmed/28977825
http://dx.doi.org/10.18632/oncotarget.18484

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617385/
https://www.ncbi.nlm.nih.gov/pubmed/28977825
http://dx.doi.org/10.18632/oncotarget.18484

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