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Decreased WWOX expression promotes angiogenesis in osteosarcoma

WWOX (WW domain-containing oxidoreductase) is known to be an important tumor suppressor in cancer. In this study, we used samples from 201 osteosarcoma patients to investigate the effects of WWOX on angiogenesis and invasion. WWOX levels were negatively correlated with RUNX2 and VEGF levels, but wer...

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Detalles Bibliográficos
Autores principales: Wen, Jia, Xu, Zongchao, Li, Jiazhen, Zhang, Yingqiang, Fan, Wenzhe, Wang, Yu, Lu, Mingjian, Li, Jiaping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617394/
https://www.ncbi.nlm.nih.gov/pubmed/28977834
http://dx.doi.org/10.18632/oncotarget.17126