Genetic defects of the IRF1-mediated major histocompatibility complex class I antigen presentation pathway occur prevalently in the JAK2 gene in non-small cell lung cancer

Recognition of major histocompatibility complex (MHC) class I antigens on tumor cells by cytotoxic T cells is involved in T cell-mediated tumor immune surveillance and immune checkpoint therapy. The interferon-γ (IFNγ)-IRF1 signaling pathway regulates MHC class I antigen presentation. To examine gen...

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Detalles Bibliográficos
Autores principales: Shen, Tao, Chen, Zhengming, Zhao, Zhizhuang Joe, Wu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617399/
https://www.ncbi.nlm.nih.gov/pubmed/28977839
http://dx.doi.org/10.18632/oncotarget.17689

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617399/
https://www.ncbi.nlm.nih.gov/pubmed/28977839
http://dx.doi.org/10.18632/oncotarget.17689

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