Sirtuin 6 inhibits epithelial to mesenchymal transition during idiopathic pulmonary fibrosis via inactivating TGF-β1/Smad3 signaling

Sirt6 which is implicated in the control of aging, cancer, and metabolism, has been shown to have anti-fibrosis function in heart and liver. However, whether Sirt6 inhibits idiopathic pulmonary fibrosis remains elusive. Epithelial to mesenchymal transition has been found to be involved in the pathog...

Descripción completa

Detalles Bibliográficos
Autores principales: Tian, Kunming, Chen, Panpan, Liu, Zhiping, Si, Shutian, Zhang, Qian, Mou, Yong, Han, Lianyong, Wang, Qin, Zhou, Xue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617402/
https://www.ncbi.nlm.nih.gov/pubmed/28977842
http://dx.doi.org/10.18632/oncotarget.17723

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617402/
https://www.ncbi.nlm.nih.gov/pubmed/28977842
http://dx.doi.org/10.18632/oncotarget.17723

Ejemplares similares