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Orphan nuclear receptor Nur77 inhibits poly (I:C)-triggered acute liver inflammation by inducing the ubiquitin-editing enzyme A20

Inflammation is a key contributor to various types of acute and chronic liver disease. We recently reported that lack of Nur77, an orphan nuclear receptor, contributes to the pathogenesis of inflammatory diseases including inflammatory bowel disease and sepsis. However, whether Nur77 plays a critica...

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Detalles Bibliográficos
Autores principales: Li, Xiu-Ming, Yang, Tian-Yu, He, Xiao-Shun, Wang, Jing-Ru, Gan, Wen-Juan, Zhang, Shen, Li, Jian-Ming, Wu, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617403/
https://www.ncbi.nlm.nih.gov/pubmed/28977843
http://dx.doi.org/10.18632/oncotarget.17731