Endoplasmic reticulum stress induces autophagy and apoptosis while inhibiting proliferation and drug resistance in multiple myeloma through the PI3K/Akt/mTOR signaling pathway

We investigated the effects of endoplasmic reticulum stress (ERS) on autophagy, proliferation, apoptosis, and drug resistance in multiple myeloma (MM). MM patients enrolled in our study (n = 268) were classified into sensitive and resistant groups based on chemotherapy efficacy, and their serum leve...

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Detalles Bibliográficos
Autores principales: Fu, Yun-Feng, Liu, Xiao, Gao, Meng, Zhang, Ya-Nan, Liu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617409/
https://www.ncbi.nlm.nih.gov/pubmed/28977849
http://dx.doi.org/10.18632/oncotarget.17862

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617409/
https://www.ncbi.nlm.nih.gov/pubmed/28977849
http://dx.doi.org/10.18632/oncotarget.17862

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