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Endoplasmic reticulum stress induces autophagy and apoptosis while inhibiting proliferation and drug resistance in multiple myeloma through the PI3K/Akt/mTOR signaling pathway

We investigated the effects of endoplasmic reticulum stress (ERS) on autophagy, proliferation, apoptosis, and drug resistance in multiple myeloma (MM). MM patients enrolled in our study (n = 268) were classified into sensitive and resistant groups based on chemotherapy efficacy, and their serum leve...

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Detalles Bibliográficos
Autores principales:	Fu, Yun-Feng, Liu, Xiao, Gao, Meng, Zhang, Ya-Nan, Liu, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617409/ https://www.ncbi.nlm.nih.gov/pubmed/28977849 http://dx.doi.org/10.18632/oncotarget.17862

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