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Clinically relevant morphological structures in breast cancer represent transcriptionally distinct tumor cell populations with varied degrees of epithelial-mesenchymal transition and CD44(+)CD24(-) stemness

Intratumor morphological heterogeneity in breast cancer is represented by different morphological structures (tubular, alveolar, solid, trabecular, and discrete) and contributes to poor prognosis; however, the mechanisms involved remain unclear. In this study, we performed 3D imaging, laser microdis...

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Detalles Bibliográficos
Autores principales: Denisov, Evgeny V., Skryabin, Nikolay A., Gerashchenko, Tatiana S., Tashireva, Lubov A., Wilhelm, Jochen, Buldakov, Mikhail A., Sleptcov, Aleksei A., Lebedev, Igor N., Vtorushin, Sergey V., Zavyalova, Marina V., Cherdyntseva, Nadezhda V., Perelmuter, Vladimir M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617414/
https://www.ncbi.nlm.nih.gov/pubmed/28977854
http://dx.doi.org/10.18632/oncotarget.18022