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Cytotoxic profiling of artesunic and betulinic acids and their synthetic hybrid compound on neurons and gliomas

Gliomas are brain-born tumors with devastating impact on their brain microenvironment. Novel approaches employ multiple combinations of chemical compounds in synthetic hybrid molecules to target malignant tumors. Here, we report on the chemical hybridization approach exemplified by artesunic acid (A...

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Detalles Bibliográficos
Autores principales: Ackermann, Annemarie, Karagöz, Aysun Çapcı, Ghoochani, Ali, Buchfelder, Michael, Eyüpoglu, Ilker, Tsogoeva, Svetlana B., Savaskan, Nicolai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617437/
https://www.ncbi.nlm.nih.gov/pubmed/28977877
http://dx.doi.org/10.18632/oncotarget.18390