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MicroRNA-145 induces apoptosis of glioma cells by targeting BNIP3 and Notch signaling

MicroRNAs (miRNAs) are involved in the pathogenesis of various human cancers. Here we show that miR-145 expression is decreased in human glioma samples, rat glioma tissues, and glioma cell lines, while expression of BNIP3 is increased. Over-expression of miR-145 or suppression of BNIP3 induced gliom...

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Detalles Bibliográficos
Autores principales: Du, Yan, Li, Juan, Xu, Tao, Zhou, Dan-Dan, Zhang, Lei, Wang, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617441/
https://www.ncbi.nlm.nih.gov/pubmed/28977881
http://dx.doi.org/10.18632/oncotarget.18604