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Silencing IGFBP-2 decreases pancreatic cancer metastasis and enhances chemotherapeutic sensitivity

Pancreatic cancer has remained one of the most devastating and lethal malignancies characterized by local invasion, distant metastasis and a high degree of chemoresistance. Insulin-like growth factor binding protein 2 (IGFBP-2) is a member of the IGFBP family of proteins, and it is highly expressed...

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Detalles Bibliográficos
Autores principales: Liu, Huan, Li, Le, Chen, Hua, Kong, Rui, Pan, Shangha, Hu, Jisheng, Wang, Yongwei, Li, Yilong, Sun, Bei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617455/
https://www.ncbi.nlm.nih.gov/pubmed/28977895
http://dx.doi.org/10.18632/oncotarget.18669