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STAT3 mutation impacts biological and clinical features of T-LGL leukemia

STAT3 mutations have been described in 30-40% of T-large granular lymphocyte (T-LGL) leukemia patients, leading to STAT3 pathway activation. Considering the heterogeneity of the disease and the several immunophenotypes that LGL clone may express, the aim of this work was to evaluate whether STAT3 mu...

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Detalles Bibliográficos
Autores principales: Teramo, Antonella, Barilà, Gregorio, Calabretto, Giulia, Ercolin, Chiara, Lamy, Thierry, Moignet, Aline, Roussel, Mikael, Pastoret, Cédric, Leoncin, Matteo, Gattazzo, Cristina, Cabrelle, Anna, Boscaro, Elisa, Teolato, Sara, Pagnin, Elisa, Berno, Tamara, De March, Elena, Facco, Monica, Piazza, Francesco, Trentin, Livio, Semenzato, Gianpietro, Zambello, Renato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617471/
https://www.ncbi.nlm.nih.gov/pubmed/28977911
http://dx.doi.org/10.18632/oncotarget.18711