Redox-dependent modulation of metformin contributes to enhanced sensitivity of esophageal squamous cell carcinoma to cisplatin

Glutathione is the major intracellular anti-oxidant against reactive oxygen species and serves as a detoxification essential. The anti-diabetic drug metformin has been showed to exert anti-tumor activity via modulation of redox homeostasis. In this study, we provided evidence that metformin inhibits...

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Detalles Bibliográficos
Autores principales: Li, Pin Dong, Liu, Zhao, Cheng, Tian Tian, Luo, Wen Guang, Yao, Jing, Chen, Jing, Zou, Zhen Wei, Chen, Li Li, Ma, Charlie, Dai, Xiao Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617486/
https://www.ncbi.nlm.nih.gov/pubmed/28977926
http://dx.doi.org/10.18632/oncotarget.18907

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617486/
https://www.ncbi.nlm.nih.gov/pubmed/28977926
http://dx.doi.org/10.18632/oncotarget.18907

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