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CTCF promotes epithelial ovarian cancer metastasis by broadly controlling the expression of metastasis-associated genes

CCCTC-binding factor (CTCF) functions as both an oncogenic and a tumor suppressor, depending on the cancer type, through epigenetic regulation. Epigenetic regulation plays a key role in cancer metastasis. Our objective was to investigate whether CTCF plays a crucial role in epithelial ovarian cancer...

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Detalles Bibliográficos
Autores principales: Zhao, Lintao, Yang, Yang, Yin, Shigang, Yang, Tao, Luo, Jing, Xie, Rongkai, Long, Haixia, Jiang, Lubin, Zhu, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617499/
https://www.ncbi.nlm.nih.gov/pubmed/28977939
http://dx.doi.org/10.18632/oncotarget.19216