The molecular basis of targeting PFKFB3 as a therapeutic strategy against cancer

6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatases (PFKFBs) are bifunctional enzymes which regulate the transformation between fructose-2, 6-bisphosphate (F2, 6BP) and fructose-6-phosphate (F6P) in the process of glucose metabolism. Among the four isozymes (PFKFB1-4), PFKFB3 has stronger kinase...

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Detalles Bibliográficos
Autores principales: Lu, Luo, Chen, Yaoyu, Zhu, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617549/
https://www.ncbi.nlm.nih.gov/pubmed/28977989
http://dx.doi.org/10.18632/oncotarget.19513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617549/
https://www.ncbi.nlm.nih.gov/pubmed/28977989
http://dx.doi.org/10.18632/oncotarget.19513

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