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Biochemical adaptations of the retina and retinal pigment epithelium support a metabolic ecosystem in the vertebrate eye

Here we report multiple lines of evidence for a comprehensive model of energy metabolism in the vertebrate eye. Metabolic flux, locations of key enzymes, and our finding that glucose enters mouse and zebrafish retinas mostly through photoreceptors support a conceptually new model for retinal metabol...

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Detalles Bibliográficos
Autores principales: Kanow, Mark A, Giarmarco, Michelle M, Jankowski, Connor SR, Tsantilas, Kristine, Engel, Abbi L, Du, Jianhai, Linton, Jonathan D, Farnsworth, Christopher C, Sloat, Stephanie R, Rountree, Austin, Sweet, Ian R, Lindsay, Ken J, Parker, Edward D, Brockerhoff, Susan E, Sadilek, Martin, Chao, Jennifer R, Hurley, James B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617631/
https://www.ncbi.nlm.nih.gov/pubmed/28901286
http://dx.doi.org/10.7554/eLife.28899