Acid Sphingomyelinase Inhibition Prevents Development of Sepsis Sequelae in the Murine Liver

The molecular mechanisms of maladaptive response in liver tissue with respect to the acute and post-acute phase of sepsis are not yet fully understood. Long-term sepsis survivors might develop hepatocellular/hepatobiliary injury and fibrosis. Here, we demonstrate that acid sphingomyelinase, an impor...

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Detalles Bibliográficos
Autores principales: Chung, Ha-Yeun, Witt, C. Julius, Jbeily, Nayla, Hurtado-Oliveros, Jorge, Giszas, Benjamin, Lupp, Amelie, Gräler, Markus H., Bruns, Tony, Stallmach, Andreas, Gonnert, Falk A., Claus, Ralf A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617833/
https://www.ncbi.nlm.nih.gov/pubmed/28955042
http://dx.doi.org/10.1038/s41598-017-11837-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617833/
https://www.ncbi.nlm.nih.gov/pubmed/28955042
http://dx.doi.org/10.1038/s41598-017-11837-2

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