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Acid Sphingomyelinase Inhibition Prevents Development of Sepsis Sequelae in the Murine Liver
The molecular mechanisms of maladaptive response in liver tissue with respect to the acute and post-acute phase of sepsis are not yet fully understood. Long-term sepsis survivors might develop hepatocellular/hepatobiliary injury and fibrosis. Here, we demonstrate that acid sphingomyelinase, an impor...
Autores principales: | Chung, Ha-Yeun, Witt, C. Julius, Jbeily, Nayla, Hurtado-Oliveros, Jorge, Giszas, Benjamin, Lupp, Amelie, Gräler, Markus H., Bruns, Tony, Stallmach, Andreas, Gonnert, Falk A., Claus, Ralf A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617833/ https://www.ncbi.nlm.nih.gov/pubmed/28955042 http://dx.doi.org/10.1038/s41598-017-11837-2 |
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