MicroRNA-9 downregulates the ANO1 chloride channel and contributes to cystic fibrosis lung pathology

Cystic fibrosis results from reduced cystic fibrosis transmembrane conductance regulator protein activity leading to defective epithelial ion transport. Ca(2+)-activated Cl(−) channels mediate physiological functions independently of cystic fibrosis transmembrane conductance regulator. Anoctamin 1 (...

Descripción completa

Detalles Bibliográficos
Autores principales: Sonneville, Florence, Ruffin, Manon, Coraux, Christelle, Rousselet, Nathalie, Le Rouzic, Philippe, Blouquit-Laye, Sabine, Corvol, Harriet, Tabary, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617894/
https://www.ncbi.nlm.nih.gov/pubmed/28955034
http://dx.doi.org/10.1038/s41467-017-00813-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617894/
https://www.ncbi.nlm.nih.gov/pubmed/28955034
http://dx.doi.org/10.1038/s41467-017-00813-z

Ejemplares similares