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Inhibition of p110δ PI3K prevents inflammatory response and restenosis after artery injury

Inflammatory cells play key roles in restenosis upon vascular surgical procedures such as bypass grafts, angioplasty and stent deployment but the molecular mechanisms by which these cells affect restenosis remain unclear. The p110δ isoform of phosphoinositide 3-kinase (PI3K) is mainly expressed in w...

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Detalles Bibliográficos
Autores principales: Bilancio, Antonio, Rinaldi, Barbara, Oliviero, Maria Antonietta, Donniacuo, Maria, Monti, Maria Gaia, Boscaino, Amedeo, Marino, Irene, Friedman, Lori, Rossi, Francesco, Vanhaesebroeck, Bart, Migliaccio, Antimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617917/
https://www.ncbi.nlm.nih.gov/pubmed/28851839
http://dx.doi.org/10.1042/BSR20171112