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Physical Forces May Cause the HoxD Gene Cluster Elongation

Hox gene collinearity was discovered be Edward B. Lewis in 1978. It consists of the Hox1, Hox2, Hox3 ordering of the Hox genes in the chromosome from the telomeric to the centromeric side of the chromosome. Surprisingly, the spatial activation of the Hox genes in the ontogenetic units of the embryo...

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Detalles Bibliográficos
Autor principal: Papageorgiou, Spyros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617920/
https://www.ncbi.nlm.nih.gov/pubmed/28644379
http://dx.doi.org/10.3390/biology6030032