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The Potential of Targeting Brain Pathology with Ascl1/Mash1

The proneural factor Achaete-scute complex-like 1 (Ascl1/Mash1) acts as a pioneering transcription factor that initializes neuronal reprogramming. It drives neural progenitors and non-neuronal cells to exit the cell cycle, and promotes neuronal differentiation by activating neuronal target genes, ev...

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Detalles Bibliográficos
Autor principal: Tang, Bor Luen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617972/
https://www.ncbi.nlm.nih.gov/pubmed/28832532
http://dx.doi.org/10.3390/cells6030026