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The Potential of Targeting Brain Pathology with Ascl1/Mash1
The proneural factor Achaete-scute complex-like 1 (Ascl1/Mash1) acts as a pioneering transcription factor that initializes neuronal reprogramming. It drives neural progenitors and non-neuronal cells to exit the cell cycle, and promotes neuronal differentiation by activating neuronal target genes, ev...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617972/ https://www.ncbi.nlm.nih.gov/pubmed/28832532 http://dx.doi.org/10.3390/cells6030026 |