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Identification of Staphylococcus aureus Cellular Pathways Affected by the Stilbenoid Lead Drug SK-03-92 Using a Microarray

The mechanism of action for a new lead stilbene compound coded SK-03-92 with bactericidal activity against methicillin-resistant Staphylococcus aureus (MRSA) is unknown. To gain insight into the killing process, transcriptional profiling was performed on SK-03-92 treated vs. untreated S. aureus. Fou...

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Detalles Bibliográficos
Autores principales: Schwan, William R., Polanowski, Rebecca, Dunman, Paul M., Medina-Bielski, Sara, Lane, Michelle, Rott, Marc, Lipker, Lauren, Wescott, Amy, Monte, Aaron, Cook, James M., Baumann, Douglas D., Tiruveedhula, V.V.N. Phani Babu, Witzigmann, Christopher M., Mikel, Cassandra, Rahman, Md Toufiqur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617981/
https://www.ncbi.nlm.nih.gov/pubmed/28892020
http://dx.doi.org/10.3390/antibiotics6030017