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Synthesis and Immunological Evaluation of Virus-Like Particle-Milbemycin A(3)/A(4) Conjugates
Milbemycins are macrolide antibiotics with a broad spectrum of nematocidal, insecticidal, and acaricidal activity. To obtain milbemycin A(3)/A(4) derivatives suitable for chemical conjugation to protein carriers (milbemycin haptens), succinate linker and a novel 17-atom-long linker containing a term...
Autores principales: | Zeltins, Andris, Turks, Māris, Skrastina, Dace, Lugiņina, Jevgeņija, Kalnciema, Ieva, Balke, Ina, Bizdēna, Ērika, Skrivelis, Vitalijs |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617982/ https://www.ncbi.nlm.nih.gov/pubmed/28892001 http://dx.doi.org/10.3390/antibiotics6030018 |
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