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Analysis of Class I Major Histocompatibility Complex Gene Transcription in Human Tumors Caused by Human Papillomavirus Infection

Oncoproteins from high-risk human papillomaviruses (HPV) downregulate the transcription of the class I major histocompatibility complex (MHC-I) antigen presentation apparatus in tissue culture model systems. This could allow infected or transformed cells to evade the adaptive immune response. Using...

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Detalles Bibliográficos
Autores principales: Gameiro, Steven F., Zhang, Ali, Ghasemi, Farhad, Barrett, John W., Nichols, Anthony C., Mymryk, Joe S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618018/
https://www.ncbi.nlm.nih.gov/pubmed/28891951
http://dx.doi.org/10.3390/v9090252