Silencing of NRF2 Reduces the Expression of ALDH1A1 and ALDH3A1 and Sensitizes to 5-FU in Pancreatic Cancer Cells

Pancreatic cancer remains an intractable cancer with a poor five-year survival rate, which requires new therapeutic modalities based on the biology of pancreatic oncogenesis. Nuclear factor E2 related factor-2 (NRF2), a key cytoprotective nuclear transcription factor, regulates antioxidant productio...

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Detalles Bibliográficos
Autores principales: Duong, Hong-Quan, You, Kyu Sic, Oh, Seunghoon, Kwak, Sahng-June, Seong, Yeon-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618080/
https://www.ncbi.nlm.nih.gov/pubmed/28671577
http://dx.doi.org/10.3390/antiox6030052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618080/
https://www.ncbi.nlm.nih.gov/pubmed/28671577
http://dx.doi.org/10.3390/antiox6030052

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