High Dose Ascorbate Causes Both Genotoxic and Metabolic Stress in Glioma Cells

We have previously shown that exposure to high dose ascorbate causes double stranded breaks (DSBs) and a build-up in S-phase in glioblastoma (GBM) cell lines. Here we investigated whether or not this was due to genotoxic stress as well as metabolic stress generated by exposure to high dose ascorbate...

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Detalles Bibliográficos
Autores principales: Castro, Maria Leticia, Carson, Georgia M., McConnell, Melanie J., Herst, Patries M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618086/
https://www.ncbi.nlm.nih.gov/pubmed/28737676
http://dx.doi.org/10.3390/antiox6030058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618086/
https://www.ncbi.nlm.nih.gov/pubmed/28737676
http://dx.doi.org/10.3390/antiox6030058

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