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High Dose Ascorbate Causes Both Genotoxic and Metabolic Stress in Glioma Cells
We have previously shown that exposure to high dose ascorbate causes double stranded breaks (DSBs) and a build-up in S-phase in glioblastoma (GBM) cell lines. Here we investigated whether or not this was due to genotoxic stress as well as metabolic stress generated by exposure to high dose ascorbate...
Autores principales: | Castro, Maria Leticia, Carson, Georgia M., McConnell, Melanie J., Herst, Patries M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618086/ https://www.ncbi.nlm.nih.gov/pubmed/28737676 http://dx.doi.org/10.3390/antiox6030058 |
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