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Azidophenyl as a click-transformable redox label of DNA suitable for electrochemical detection of DNA–protein interactions

New redox labelling of DNA by an azido group which can be chemically transformed to nitrophenyltriazole or silenced to phenyltriazole was developed and applied to the electrochemical detection of DNA–protein interactions. 5-(4-Azidophenyl)-2′-deoxycytidine and 7-(4-azidophenyl)-7-deaza-2′-deoxyadeno...

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Detalles Bibliográficos
Autores principales: Balintová, Jana, Špaček, Jan, Pohl, Radek, Brázdová, Marie, Havran, Luděk, Fojta, Miroslav, Hocek, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618110/
https://www.ncbi.nlm.nih.gov/pubmed/28970873
http://dx.doi.org/10.1039/c4sc01906g