Cargando…

Thermal Stability of Phase-Separated Domains in Multicomponent Lipid Membranes with Local Anesthetics

The functional mechanisms of local anesthetics (LAs) have not yet been fully explained, despite their importance in modern medicine. Recently, an indirect interaction between channel proteins and LAs was proposed as follows: LAs alter the physical properties of lipid membranes, thus affecting the ch...

Descripción completa

Detalles Bibliográficos
Autores principales: Sugahara, Ko, Shimokawa, Naofumi, Takagi, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618118/
https://www.ncbi.nlm.nih.gov/pubmed/28661445
http://dx.doi.org/10.3390/membranes7030033