Block V RTX Domain of Adenylate Cyclase from Bordetella pertussis: A Conformationally Dynamic Scaffold for Protein Engineering Applications

The isolated Block V repeats-in-toxin (RTX) peptide domain of adenylate cyclase (CyaA) from Bordetella pertussis reversibly folds into a β-roll secondary structure upon calcium binding. In this review, we discuss how the conformationally dynamic nature of the peptide is being engineered and employed...

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Detalles Bibliográficos
Autores principales: Bulutoglu, Beyza, Banta, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618222/
https://www.ncbi.nlm.nih.gov/pubmed/28926974
http://dx.doi.org/10.3390/toxins9090289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618222/
https://www.ncbi.nlm.nih.gov/pubmed/28926974
http://dx.doi.org/10.3390/toxins9090289

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