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Coupling TOR to the Cell Cycle by the Greatwall–Endosulfine–PP2A-B55 Pathway

Cell growth and division are two processes tightly coupled in proliferating cells. While Target of Rapamycin (TOR) is the master regulator of growth, the cell cycle is dictated by the activity of the cyclin-dependent kinases (CDKs). A long-standing question in cell biology is how these processes may...

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Detalles Bibliográficos
Autores principales: Pérez-Hidalgo, Livia, Moreno, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618240/
https://www.ncbi.nlm.nih.gov/pubmed/28777780
http://dx.doi.org/10.3390/biom7030059