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Development of Phosphorothioate DNA and DNA Thioaptamers
Nucleic acid aptamers are short RNA- or DNA-based affinity reagents typically selected from combinatorial libraries to bind to a specific target such as a protein, a small molecule, whole cells or even animals. Aptamers have utility in the development of diagnostic, imaging and therapeutic applicati...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618299/ https://www.ncbi.nlm.nih.gov/pubmed/28703779 http://dx.doi.org/10.3390/biomedicines5030041 |