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Development of Phosphorothioate DNA and DNA Thioaptamers

Nucleic acid aptamers are short RNA- or DNA-based affinity reagents typically selected from combinatorial libraries to bind to a specific target such as a protein, a small molecule, whole cells or even animals. Aptamers have utility in the development of diagnostic, imaging and therapeutic applicati...

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Detalles Bibliográficos
Autores principales: Volk, David E., Lokesh, Ganesh L. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618299/
https://www.ncbi.nlm.nih.gov/pubmed/28703779
http://dx.doi.org/10.3390/biomedicines5030041