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Aptamer-siRNA Chimeras: Discovery, Progress, and Future Prospects
Synthetic nucleic acid ligands (aptamers) have emerged as effective delivery tools for many therapeutic oligonucleotide-based drugs, including small interfering RNAs (siRNAs). In this review, we summarize recent progress in the aptamer selection technology that has made possible the identification o...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618303/ https://www.ncbi.nlm.nih.gov/pubmed/28792479 http://dx.doi.org/10.3390/biomedicines5030045 |