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Ciguatoxins Evoke Potent CGRP Release by Activation of Voltage-Gated Sodium Channel Subtypes Na(V)1.9, Na(V)1.7 and Na(V)1.1

Ciguatoxins (CTXs) are marine toxins that cause ciguatera fish poisoning, a debilitating disease dominated by sensory and neurological disturbances that include cold allodynia and various painful symptoms as well as long-lasting pruritus. Although CTXs are known as the most potent mammalian sodium c...

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Detalles Bibliográficos
Autores principales: Touska, Filip, Sattler, Simon, Malsch, Philipp, Lewis, Richard J., Reeh, Peter W., Zimmermann, Katharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618408/
https://www.ncbi.nlm.nih.gov/pubmed/28867800
http://dx.doi.org/10.3390/md15090269