Pharmacokinetics of Jaspine B and Enhancement of Intestinal Absorption of Jaspine B in the Presence of Bile Acid in Rats

We aimed to investigate the pharmacokinetics and the underlying mechanisms of the intestinal absorption, distribution, metabolism, and excretion of Jaspine B in rats. The oral bioavailability of Jaspine B was 6.2%, but it decreased to 1.6% in bile-depleted rats and increased to 41.2% (normal) and 23...

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Detalles Bibliográficos
Autores principales: Choi, Min-Koo, Lee, Jihoon, Nam, So Jeong, Kang, Yun Ju, Han, Youjin, Choi, Kwangik, Choi, Young A., Kwon, Mihwa, Lee, Dongjoo, Song, Im-Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618418/
https://www.ncbi.nlm.nih.gov/pubmed/28862650
http://dx.doi.org/10.3390/md15090279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618418/
https://www.ncbi.nlm.nih.gov/pubmed/28862650
http://dx.doi.org/10.3390/md15090279

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