Human CD3+ T-Cells with the Anti-ERBB2 Chimeric Antigen Receptor Exhibit Efficient Targeting and Induce Apoptosis in ERBB2 Overexpressing Breast Cancer Cells

Breast cancer is a common malignancy among women. The innate and adaptive immune responses failed to be activated owing to immune modulation in the tumour microenvironment. Decades of scientific study links the overexpression of human epidermal growth factor receptor 2 (ERBB2) antigen with aggressiv...

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Detalles Bibliográficos
Autores principales: Munisvaradass, Rusheni, Kumar, Suresh, Govindasamy, Chandramohan, Alnumair, Khalid S., Mok, Pooi Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618474/
https://www.ncbi.nlm.nih.gov/pubmed/28885562
http://dx.doi.org/10.3390/ijms18091797

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618474/
https://www.ncbi.nlm.nih.gov/pubmed/28885562
http://dx.doi.org/10.3390/ijms18091797

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