Contribution of Intrinsic Lactate to Maintenance of Seizure Activity in Neocortical Slices from Patients with Temporal Lobe Epilepsy and in Rat Entorhinal Cortex

Neuronal lactate uptake supports energy metabolism associated with synaptic signaling and recovery of extracellular ion gradients following neuronal activation. Altered expression of the monocarboxylate transporters (MCT) in temporal lobe epilepsy (TLE) hampers lactate removal into the bloodstream....

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Detalles Bibliográficos
Autores principales: Angamo, Eskedar Ayele, Haq, Rizwan ul, Rösner, Jörg, Gabriel, Siegrun, Gerevich, Zoltán, Heinemann, Uwe, Kovács, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618484/
https://www.ncbi.nlm.nih.gov/pubmed/28832554
http://dx.doi.org/10.3390/ijms18091835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618484/
https://www.ncbi.nlm.nih.gov/pubmed/28832554
http://dx.doi.org/10.3390/ijms18091835

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