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Negative Correlation between the Diffusion Coefficient and Transcriptional Activity of the Glucocorticoid Receptor
The glucocorticoid receptor (GR) is a transcription factor, which interacts with DNA and other cofactors to regulate gene transcription. Binding to other partners in the cell nucleus alters the diffusion properties of GR. Raster image correlation spectroscopy (RICS) was applied to quantitatively cha...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618504/ https://www.ncbi.nlm.nih.gov/pubmed/28841150 http://dx.doi.org/10.3390/ijms18091855 |