Cargando…

Negative Correlation between the Diffusion Coefficient and Transcriptional Activity of the Glucocorticoid Receptor

The glucocorticoid receptor (GR) is a transcription factor, which interacts with DNA and other cofactors to regulate gene transcription. Binding to other partners in the cell nucleus alters the diffusion properties of GR. Raster image correlation spectroscopy (RICS) was applied to quantitatively cha...

Descripción completa

Detalles Bibliográficos
Autores principales: Mikuni, Shintaro, Yamamoto, Johtaro, Horio, Takashi, Kinjo, Masataka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618504/
https://www.ncbi.nlm.nih.gov/pubmed/28841150
http://dx.doi.org/10.3390/ijms18091855